Number of natural killer cells and cytokine levels in peripheral blood at various degrees of severity
نویسندگان
چکیده
This study aims to investigate NK cell number and cytokines level in various degrees of severity COVID-19 cases. A total 63 patient aged >18 y were divided into mild-moderate severe-critical groups. Patient characteristics peripheral blood count obtained from medical records. cells number, levels IFN-?, IL-10, IL-12 examined by means flow cytometry. The group had leukocytosis, neutrophilia, lymphopenia, higher Neutrophil Lymphocyte Ratio, lower IL-10. In group, those >60 years both groups, patients with diabetes comorbidities a (p<0.05). IL-10 have potential as predictor severe patients.
منابع مشابه
Expression of Th1 and Th2 Cytokine and Associated Transcription Factors in Peripheral Blood Mononuclear Cells and Correlation with Disease Severity
Background: Psoriasis is a T cell-mediated autoimmune disease with elevated level of pro-inflammatory cytokines belonging mainly to Th1 pathway. We investigated whether treatment with micronutrients along with methotrexate (MTX) is able to modulate mRNA expression of Th1 and Th2 patterns and its correlation with disease severity. Methods: Thirty plaque type psoriasis patients with Psoriasis ...
متن کاملThe State of Peripheral Blood Natural Killer Cells and Cytotoxicity in Women with Recurrent Pregnancy Loss and Unexplained Infertility
Objective : The prognostic value of peripheral natural killer (pNK) cells, as a screening test in women with recurrent pregnancy loss (RPL) and unexplained infertility is still a matter for discussion. The aim of this study was to compare the percentage of circulating CD56+NK cells, CD69 and perforin markers between women with unexplained infertility and RPL with healthy control group. Material...
متن کاملevaluation of cd56dim and cd56bright natural killer cells in peripheral blood of women with ivf failures
background: infertility is an increasing medical and social problem. in vitro fertilization (ivf) has become a common and accessible treatment for a wide variety of indications that have variable outcomes. natural killer (nk) cells have been identified as relevant immunological factors involved in reproductive success or failure. objective: the aim of this study was to compare the percentage of...
متن کاملthe role of application of dynamic assessment approach in improvement of iranian efl writing performance at different language proficiency levels
the present study sought to investigate the role of dynamic assessment (da) in improvement of iranian efl writing performance at different language proficiency levels. to this end, after conducting the quick placement test, 60 iranian efl learners were assigned to two groups with different language proficiency levels. in both groups each participant wrote two compositions, one before and one af...
THE CYTOTOXICITY PATHWAY OF NATURAL KILLER CELLS IN CORD BLOOD COMPARED TO P ERIPHERAL BLOOD
The cytotoxic activity of natural killer cells is usually tested by radioactive assay CSI Cr release assay), which detects the release of cytoplasmic contents after plasma membrane disintegration of dying cells. In contrast to this indirect evaluation of cytotoxicity, the assessment of cell damage by flow cytometry aims to provide a more exact characterization of the death pathway via detec...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Communications in science and technology
سال: 2023
ISSN: ['2502-9266', '2502-9258']
DOI: https://doi.org/10.21924/cst.8.1.2023.1106